The proposals comprise an extension of the railway station, a new station entrance, enlarged concourse as well as works to improve access to the station, including a new footbridge to Hale Village.
The Council's planning officers said in the committee report that there was "strong strategic and local level policy support for the improvement of the station interchange at Tottenham Hale to support and contribute to the regeneration aims for this area".
They said the proposals would create an "attractive landmark station" which would make a significant contribution to improving public realm and assist the wider regeneration aims for the area.
Tottenham Hale is located within the Upper Lea Valley area, which has been identified as a key area for growth and has capacity for the creation of 15,000 new jobs and 20,100 new homes.
"The decision to approve TfL's proposals for Tottenham Hale station is fantastic news and an exciting outcome for local residents and station users," said TfL managing director for planning Michele Dix in a statement.
Dix said that the planned improvements will "reduce crowding and queuing at the station, saving passengers' time when interchanging between National Rail operated by Greater Anglia and Tube services, as well as improving the station ambience and increasing the retail units".
