The plan sets out a proposed strategy for the delivery of at least 2,800 new homes as well as 180,000 square metres of employment space, including offices and research and development space, and 20,000 sq m of retail space, with 7,700 jobs to be generated.
It also sets out a strategy for a range of transport measures to mitigate the impact of HS2, including public transport enhancements and measures to promote walking and cycling.
Johnson said in a statement that the key aim of the plan is to minimise the impact the proposed HS2 scheme will have on the area and to realise the area's economic potential.
Camden Council said that, although it opposes HS2, it acknowledges the need to work "effectively" with political parties, local community groups, the Mayor of London, the Department for Transport and HS2 "to secure the best for deal for local communities by maximising the benefits of a redeveloped Euston".
The area around Euston has been earmarked as a location for jobs and homes in Camden's Core Strategy and in the GLA's London Plan, which identifies it as an Opportunity Area with potential for the creation of 5,000 jobs and 1,000 new homes.
Johnson said that, although he has always been "clear about his support for high speed rail", he maintains that there are "certain changes" needed to make the project work for London. He said that he "remains in discussion" with the Government over the best long-term solution for Euston.
"The redevelopment of Euston offers a fantastic opportunity that could see huge regeneration and economic benefits for this part of the capital and beyond," Johnson said. "Getting the right plans in place now will help us to ensure that we get the best outcomes for local people, business and visitors to the area.
"With the potential to create thousands of jobs, new homes and an important new transport hub, it’s vitally important that everyone has their say,” he added.
The consultation will run until 7 October. Following the receipt of comments, a revised plan will be drafted which will seek to "properly balance the priorities of the local area with the economic growth potential associated with redevelopment of the station," Johnson said.
